Building Life

Founded in 2013, Arcturus is a leader in RNA medicines.

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Arcturus Therapeutics

  • Ultragenyx Pharmaceutical Inc. entered into a research collaboration and license agreement with Arcturus to discover and develop messenger RNA (mRNA) therapeutics.Ultragenyx Pharmaceutical Inc. entered into a research collaboration and license agreement with Arcturus to discover and develop messenger RNA (mRNA) therapeutics.READ MORE
  • Janssen Pharmaceuticals, Inc entered into a research collaboration and worldwide license agreement with Arcturus to develop and commercialize RNA-based drug products.Janssen Pharmaceuticals, Inc entered into a research collaboration and worldwide license agreement with Arcturus to develop and commercialize RNA-based drug products.READ MORE
  • Arbutus obtained a worldwide, non-exclusive license to a novel RNAi payload technology called Unlocked Nucleomonomer Agent (UNA) from Arcturus.Arbutus obtained a worldwide, non-exclusive license to a novel RNAi payload technology called Unlocked Nucleomonomer Agent (UNA) from Arcturus.

Proprietary Technologies

UNA and LUNAR™ Will Revolutionize RNA Medicines

TRANSPORTERS RECEPTORS ANTIBODIES ENZYMES TALEN GPCR’S HORMONES CHAPERONES CAR-T CRISPR
Trans-membrane Proteins Secreted Proteins Intracellular Proteins Engineered Antigens Engineered Nucleases
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RNA Medicines

  • Antisense RNA
    Antisense RNA works by binding to messenger RNA (mRNA) and physically preventing the cell from translating the mRNA into protein. READ MORE
  • Gene Editing
    Human DNA has roughly 20 000 genes. Each gene contains the code needed to make one or more proteins. READ MORE
  • MicroRNA
    MicroRNA medicines can be used to treat complex diseases like cancer that are caused by many different malfunctioning proteins. READ MORE
  • mRNA
    Messenger RNA (mRNA) therapeutics can treat diseases caused by a lack of protein, or by defective proteins, such as Duchenne muscular dystrophy and cystic fibrosis. READ MORE
  • RNA
    RNA medicines can target any gene or protein in humans and so can be used to treat diseases that cannot be treated by conventional drugs such as small molecules and biologics. READ MORE
  • RNAi
    RNA interference (RNAi) is a natural mechanism used by the body to turn genes off without permanently changing DNA. READ MORE
  • siRNA
    Small interfering RNA (siRNA) medicines can treat viral infections like hepatitis B and diseases like Huntington’s disease that are caused by malfunctioning proteins. READ MORE

Pipeline

name

LUNAR-OTC

indication
OTC Deficiency
api
mUNA

INTERNAL mUNA PROGRAMS

PRECLINICAL

name

LUNAR-HBV

indication
Hepatitis B
api
siUNA

PARTNERED PROGRAMS

PRECLINICAL

name

Arbutus, ARB-1467

indication
Hepatitis B
api
siUNA

LICENSED PROGRAMS

CLINICAL

News & Events

  • December 6, 2016

    Arcturus Therapeutics Announces Collaboration with Takeda Pharmaceuticals to Develop RNA–based Therapeutics for the Treatment of Nonalcoholic Steatohepatitis (NASH)

    • December 6 2016
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  • November 1, 2016

    nature Biotechnology and nature Reviews Drug Discovery

    • November 1 2016
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  • October 4, 2016

    Big Pharma Goes Small With Moves Into Incubator Space

    • October 4 2016
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  • October 3, 2016

    Arcturus Therapeutics to Report Identification of LUNAR-HBV, a Potent Combination of Three UNA Oligomers Targeting All Hepatitis B Virus Genotypes at the AASLD Liver Meeting® 2016

    • October 3 2016
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  • September 30, 2016

    November 1-2, 2016

    • September 30 2016
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  • June 1, 2016

    Arcturus Therapeutics To Present At 2016 BIO International Convention in San Francisco

    • June 1 2016
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  • March 16, 2016

    Arcturus Therapeutics Receives Intent to Grant Notice from the European Patent Office for their Unlocked Nucleomonomer Agent (UNA) Technology

    • March 16 2016
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  • January 6, 2016

    Arcturus Therapeutics Selected to Present at Biotech Showcase™ 2016

    • January 6 2016
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  • November 11, 2015

    International mRNA Health Conference

    • November 11 2015
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