Arcturus’ proprietary unlocked nucleomonomer agent (UNA) Oligomer™ technology can be used to make all types of RNA medicines more stable, safe and specific.
UNA nucleotides can be incorporated into either DNA or RNA using standard automated synthesis procedures. UNAs have a similar structure to natural nucleic acids so do not change RNA function or tertiary structure. In partnered clinical trials, RNA medicines incorporating UNAs have been shown to be safe and effective in human patients.
UNAs are not recognized by the immune system so do not stimulate an immune response and are not broken down as quickly as natural RNA. Therefore RNA medicines incorporating UNAs cause less toxicity, have less off-target effects, are more potent and have a longer half-life than regular RNA medicines.
May 15, 2017
Ernst & Young Selected Arcturus as the Finalists for the Entrepreneur Of The Year 2017 Award® in San Diego
April 29, 2017
Arcturus Therapeutics to Present at the TIDES--Oligonucleotides and Peptide Therapeutics, on Unlocked Nucleomonomer Agent (UNA) Oligomer System, Challenges and Opportunities
April 10, 2017
Arcturus Therapeutics is Selected by Ernst and Young as Semifinalists for the Entrepreneur Of The Year® 2017 Award in San Diego