MicroRNA medicines can be used to treat complex diseases like cancer that are caused by many different malfunctioning proteins.
MicroRNAs are small RNAs that naturally occur in humans, and many other animals, and regulate how much protein is made from messenger RNA (mRNA). Each microRNA can target hundreds of different mRNAs and so can regulate entire networks of genes.
MicroRNAs are one of several classes of small RNA molecules involved in a mechanism called RNA interference or RNAi. MicroRNAs, small interfering RNAs and antisense RNAs can all bind to mRNA and prevent it from being translated into protein.
However, unlike other small RNAs, microRNAs can also work to increase the amount of protein made from mRNA. This means that microRNA medicines can be used to treat diseases like cancer that have too much of some proteins but too little of others.
May 30, 2017
Arcturus Therapeutics to Receive Up to $3 Million from Cystic Fibrosis Foundation Therapeutics to Advance a Novel LUNAR-Formulated mRNA CFTR Therapeutic
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Pictures by Ernst and Young (Finalists for the Entrepreneur Of The Year 2017 Award® in San Diego)
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Arcturus Therapeutics in the list of Cystic Fibrosis Key Companies