Arcturus Therapeutics

Arcturus Therapeutics is a leading clinical-stage messenger RNA medicines company focused on the discovery, development and commercialization of therapeutics for rare diseases and vaccines. We have proprietary technologies, validating partnerships, and an experienced team with deep expertise in delivery and RNA-based therapeutics

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News & Events
March 4, 2013
Arcturus Therapeutics Begins Operations in Janssen Labs
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May 8, 2013
Arcturus Therapeutics Announces New Appointments to its Board of Directors and Scientific Advisory Board
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June 1, 2013
Arcturus Therapeutics Raises $1.3 Million in Series Seed Funding
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June 3, 2013
With $1.3M in Seed Funding, Arcturus Adds to RNAi Hub in San Diego
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June 3, 2013
RNAi therapeutics startup sets up shop at Janssen labs, closes $1.3M seed round
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June 3, 2013
Arcturus Therapeutics Raises $1.3 Million in Series Seed Funding
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June 4, 2013
Janssen Labs-based Arcturus gets $1.3M boost for RNAi delivery tech
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June 4, 2013
Arcturus Therapeutics Raises $1.3 Million in Series Seed Funding
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June 4, 2013
Startup Arcturus Pulls in $1.3M in Seed Money amid Renewed Interest in RNAi
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August 14, 2013
Arcturus Therapeutics Acquires Cutting-Edge UNA Patent Estate from Marina Biotech
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August 14, 2013
Arcturus Therapeutics Acquires Cutting-Edge UNA Patent Estate from Marina
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August 15, 2013
San Diego upstart acquires RNA tech from cash-strapped Marina Biotech
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August 15, 2013
San Diego Life Sciences Roundup: Vical, Fate, Arcturus, and More
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August 15, 2013
Arcturus Therapeutics Acquires Patent Portfolio from Marina Biotech
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August 15, 2013
Marina Sells UNA Patent Estate to Arcturus as It Looks to Resume Operations
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October 21, 2013
GenomeWeb Acturus Closes $5M Series A Round, Aims for Clinic in '15 with RNAi Drug
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December 30, 2020
Arcturus Therapeutics to Advance ARCT-032, an Aerosolized LUNAR® mRNA-based Therapeutic, as a Development Candidate for Cystic Fibrosis Lung Disease
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January 4, 2021
Arcturus Therapeutics Receives FDA Allowance to Proceed with Phase 2 Study of ARCT-021 (LUNAR-COV19) Vaccine Candidate in the United States
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January 6, 2021
Arcturus Therapeutics to Present at Upcoming Investor Conference
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February 11, 2021
Arcturus Therapeutics to Present at Upcoming Investor Conferences
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February 19, 2021
Arcturus Therapeutics to Report Fourth Quarter and Year-End 2020 Financial Results and Provide Corporate Update on March 1, 2021
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February 22, 2021
Arcturus Therapeutics Acquires Exclusive License to mRNA Manufacturing Technology from Alexion Pharmaceuticals
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March 1, 2021
Arcturus Therapeutics Announces Fourth Quarter and Full Year 2020 Financial Results and Positive Clinical Updates
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March 30, 2021
Arcturus Therapeutics to Present at Upcoming Investor and Scientific Conferences
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May 3, 2021
Arcturus Therapeutics to Report First Quarter 2021 Financial Results and Provide Corporate Update on May 10, 2021
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May 10, 2021
Arcturus Therapeutics Announces First Quarter 2021 Company Overview and Financial Results and Provides New Clinical Data
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June 9, 2021
Arcturus Therapeutics to Present at Upcoming Investor and Scientific Conferences
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July 6, 2021
Arcturus Therapeutics to Present at Upcoming Investor and Scientific Conferences
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July 26, 2021
Arcturus Therapeutics to Report Second Quarter 2021 Financial Results and Provide Corporate Update on August 9, 2021
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July 28, 2021
Arcturus Announces Regulatory Approval to Proceed with Phase 2 Study of ARCT-810 mRNA Therapeutic Candidate for Ornithine Transcarbamylase (OTC) Deficiency
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August 2, 2021
Arcturus Therapeutics Collaborates with Vingroup to Establish Manufacturing Facility in Vietnam for Arcturus’ Investigational mRNA Vaccines for COVID-19
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August 2, 2021
Arcturus Announces Approval of a Clinical Trial Application to Advance ARCT-154, a Next Generation STARR™ mRNA Vaccine Targeting the SARS-CoV-2 Delta Variant and Other Variants of Concern
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August 3, 2021
Arcturus Announces Approval of Singapore Clinical Trial Application to Advance ARCT-154 and ARCT-165, Next Generation STARR™ mRNA Vaccines Targeting SARS-CoV-2 Variants of Concern, in a Phase 1/2 Study
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August 9, 2021
Arcturus Therapeutics Announces Second Quarter 2021 Financial Results and mRNA Vaccine and Therapeutics Pipeline Progress
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September 7, 2021
Arcturus Therapeutics to Present at Upcoming Investor and Scientific Conferences
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September 8, 2021
Arcturus Therapeutics to Participate in Citi's 16th Annual BioPharma Virtual Conference 2021
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LUNAR®-mediated delivery of RNA into cells

LUNAR® particles associate with the cell membrane of a target cell of interest and quickly enter the cell via endocytosis.

Upon entering the cytosol, the LUNAR® formulations then become trapped in the endosomes.

With increased acidity as the endosome ages, a pH-mediated disruption enables release of the RNA payload following rapid biodegradation of the LUNAR®components.

Once release of the RNA into the cytosol occurs, the translational machinery can interact with the RNA and processing and/or trafficking can then take place to make functional protein.

LUNAR® lipid mediated delivery enables delivery of RNA medicines.