Arcturus Therapeutics

Founded in 2013 and based in San Diego, Arcturus Therapeutics Ltd. (NASDAQ:ARCT) is an RNA medicines company with enabling technologies – UNA Oligomer chemistry and LUNAR® lipid-mediated delivery. Arcturus’ diverse pipeline of RNA therapeutics includes programs pursuing rare diseases, Hepatitis B, non-alcoholic steatohepatitis (NASH), cystic fibrosis, and vaccines. Arcturus’ versatile RNA therapeutics platforms can be applied toward multiple types of RNA medicines including small interfering RNA, messenger RNA, replicon RNA, antisense RNA, microRNA and gene editing therapeutics. Arcturus owns LUNAR® lipid-mediated delivery and Unlocked Nucleomonomer Agent (UNA) technology including UNA Oligomers, which are covered by its extensive patent portfolio (140 patents and patent applications, issued in the U.S., Europe, Japan, China and other countries). Arcturus’ proprietary UNA technology can be used to target individual genes in the human genome, as well as viral genes, and other species for therapeutic purposes. Arcturus’ commitment to the development of novel RNA therapeutics has led to partnerships with Janssen Pharmaceuticals, Inc., part of the Janssen Pharmaceutical Companies of Johnson & Johnson, Ultragenyx Pharmaceutical, Inc., Takeda Pharmaceutical Company Limited, Synthetic Genomics Inc., CureVac AG and Cystic Fibrosis Foundation Therapeutics Inc. For more information, visit www.Arcturusrx.com, the content of which is not incorporated herein by reference.

Arcturus Therapeutics, Inc. is presently recruiting outstanding candidates with experience in the field of RNA technologies and nanoparticle sciences. Our corporate culture is dynamic, diverse, and creative. We value collaboration and teamwork. We seek individuals to join us with a genuine passion for the science behind helping to cure disease and improve the lives of patients. Please email your resume to Careers@ArcturusRx.com.

 

Senior Scientist, Drug Discovery

We are seeking a highly motivated, well-organized, and skilled Senior Scientist to join our Drug Discovery team. The successful candidate will demonstrate a strong background in cell biology, assay development and high-throughput in vitro screening. He/she will be a hands-on expert in standard biochemical, cell and molecular biology techniques, and capable of in depth assay troubleshooting. The successful candidate will work within a matrixed environment, across a portfolio of programs, providing valuable advice to team members and make significant contributions both in and out of the lab.

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Associate Director, Formulations/Process Development

The Associate Director, Formulation/Process Development will be responsible for designing, directing, planning, coordinating and troubleshooting all aspects of formulation and process development from early lead optimization to late stage development for lipid nanoparticle based formulations of nucleic acids.

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Senior Manager/Engineer, Manufacturing Tech Service

Arcturus is seeking a Senior Manager/Engineer to manage contract manufacturing operations and technology transfer for mRNA drug substance. A successful candidate in this role will be responsible for managing technology transfer of manufacturing processes to contract manufacturing organizations (CMOs) and management of GMP manufacture for clinical supply of RNA drug substances. The candidate will also support internal and external process development activities, CMO due diligence, process scale up, data trending activities, and regulatory filings. Additionally, the candidate will be required to resolve complex manufacturing issues through collaboration with the process development and manufacturing teams. They will work closely with a team of highly motivated scientists and engineers in the RNA production and analytical sciences group to enable successful GMP manufacture of mRNA drug substance.

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Senior Program Manager

Arcturus is seeking a Senior Program Manager to work with our team members to develop and maintain a Master Program Plan, to facilitate processes for handling risks, issues, scope, budgeting, expense tracking, and to document project communications, meetings, and decisions.

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Senior Research Associate, Formulation Development

The Senior Research Associate, Formulation/Process Development will focus on supporting design, development, scale-up, manufacturing, and characterization of lipid nanoparticle based nucleic acid formulations to support our emerging research pipeline. Our ideal candidate will bring experience with nanoparticle production and purification processes including tangential flow filtration (TFF – UF/DF).

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Senior Research Associate, Analytical Development

The Sr. Research Associate, Analytical Development will be responsible for routine analytical testing of RNA-based drug substances, intermediates and formulated drug products as well as for development and optimization of analytical methodologies to support an emerging research pipeline focused on treating rare diseases.

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Senior Scientist, Formulation Development

The Senior Scientist, Formulation Development will be responsible for designing, directing, planning, coordinating and troubleshooting all aspects of lipid nanoparticle based formulation development.

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Senior Research Associate, Formulation/Process Development

The Senior Research Associate, Formulation/Process Development will focus on supporting design, development, scale-up, manufacturing, and characterization of lipid nanoparticle based nucleic acid formulations to support our emerging research pipeline. Our ideal candidate will bring experience with nanoparticle production and purification processes including tangential flow filtration (TFF – UF/DF).

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Intern, Analytical Development (Part-Time)

The Analytical Intern will assist in routine analysis and characterization of drug substances, intermediates and formulated drug products. The role offers flexible hours, a collaborative learning environment and a great entry-level opportunity to work within the biotech industry.

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This position is a temporary part-time role (15-20 hours/week).

 

Shipping & Receiving Clerk (Part-Time)

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The Shipping & Receiving Clerk will receive and distribute incoming deliveries, and reconcile Purchase Orders and packing slips for incoming deliveries. Other responsibilities will include loading and unloading deliveries, assisting with outgoing freight and shipping requests (both domestic and international), and properly responding to questions and discrepancies about shipments.

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This position is a temporary part-time role (15-20 hours/week).

 

We thank all applicants for their interest. However, due to the volume of applications we receive, only shortlisted applicants will be contacted.