Arcturus’ unlocked nucleomonomer agents (UNAs) can improve the in vivo efficiency of small interfering RNA (siRNA)-mediated gene silencing and potentially improve the efficiency of messenger RNA (mRNA)-mediated protein replacement. UNAs are RNA analogues in which the C2′-C3′ bond of the ribose ring is absent (see figure below).
One or more UNAs can be positioned strategically along a nucleic acid strand to manipulate the chemical properties of the molecule. Addition of a single UNA in siRNA therapeutics can enable more efficient suppression of target protein production.
November 7, 2018
Arcturus Therapeutics Provides Corporate Update and Reports Third Quarter 2018 Financial Results
November 5, 2018
Arcturus Therapeutics Hosts Ribbon Cutting Ceremony for its Research and Development Facility
October 1, 2018
Arcturus Therapeutics Reports Second Quarter 2018 Financial Results and Provides Corporate Update